By Hiroshi Kase
This e-book is the 1st definitive evaluation on adenosine receptor antagonists and their software to the therapy of Parkinson's ailment. The impression of those novel non-dopamine medications on vitro and in vivo structures essentially exhibits their power for the therapy of this debilitating disorder. This booklet covers how the Parkinson's disorder antagonist drug, A2A, has been researched, built, and proven. it truly is a necessary booklet for researchers drawn to the basal ganglia, purine biology, and Parkinson's sickness. Key beneficial properties* Discusses the invention and improvement of a singular non-dopaminomimetic agent for Parkinson's illness* presents the 1st definitive evaluate of adenosine antagonists and their function within the therapy of Parkinson's ailment* offers a brand new mechanism of motion of adenosine A2A receptor antagonists in motor functionProposes a speculation of adenosine A2A receptor functionality within the striatum* accomplished evaluate of adenosine, its receptor subtypes, their antagonists/agonists from biochemistry, molecular biology, medicinal chemistry, body structure, pharmacology, and neurochemistry viewpoints
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Additional resources for Adenosine Receptors and Parkinson's Disease
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Adenosine Receptors and Parkinson's Disease by Hiroshi Kase