Download PDF by David Rollinson, S.I. Hay: Advances in Parasitology, Vol. 66

By David Rollinson, S.I. Hay

ISBN-10: 0123742293

ISBN-13: 9780123742292

First released in 1963, Advances in Parasitology includes accomplished and up to date experiences in all parts of curiosity in modern parasitology. Advances in Parasitology comprises scientific reports on parasites of significant effect, similar to Plasmodium falciparum and trypanosomes. The sequence additionally includes stories of extra conventional parts, similar to zoology, taxonomy, and lifestyles historical past, which form present considering and purposes. Eclectic volumes are supplemented via thematic volumes on a number of issues together with distant Sensing and Geographical details platforms in Epidemiology and The Evolution of Parasitism--A phylogenetic persepective.

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The Chesson strain usually produces an infection with several closely-spaced attacks, whereas the St. Elizabeth strain infection exhibits an early primary attack, several months of latency and a series of late attacks in close succession . . Volunteers infected with the Chesson and St. Elizabeth strains of P. , 1950). , 1950b). It is disconcerting to realize how recently the hypnozoite stage of P. vivax was discovered (see below) and how little progress has been made since then in understanding how hypnozoite formation and reactivation is controlled; the inability to culture P.

The complexity of the presence of multiple strains is such that the features of this study are only significant in a clinical light, and cannot be applied to the duration or study of immunity of a single strain infection’ (Hill and Amatuzio, 1949). The concept of multiple concurrent, superinfecting, interacting strains had implications for epidemiology and control as well as for clinical and immunological understanding. For an individual, the presence of ‘an unknown number of strains without any cross-immunity to speak of among them [implied that] only by chance is he infected twice in succession with the same kind of parasite, and his individual malaria season draws to a close only when he has solidified anew his resistance to the principal strains which are in the air around him every night.

If so, perhaps, ‘every second, third or fourth infected Anopheles mosquito bite which is prevented means the avoidance of one, two or three relapses later on’ (Horing, 1947), with different strains. An attempt to integrate the evidence hypothesized that ‘when pre-erythrocytic parasites are discharged from an exo-erythrocytic depot, there may be several strains amongst them but one strain predominates . . [and] immunity develops against the predominating strain, but, since there will be some overlapping of the antigenic patterns, there may also be some, possibly transient, cross-immunity against other strains.

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Advances in Parasitology, Vol. 66 by David Rollinson, S.I. Hay

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